Interplay between spinodal decomposition and glass formation in proteins exhibiting short-range attractions

被引：186

作者：

Cardinaux, Frederic ^{[1
]}

Gibaud, Thomas ^{[1
]}

Stradner, Anna ^{[1
]}

Schurtenberger, Peter ^{[1
]}

机构：

[1] Univ Fribourg, Dept Phys, CH-1700 Fribourg, Switzerland

来源：

PHYSICAL REVIEW LETTERS | 2007年 / 99卷 / 11期

关键词：

D O I：

10.1103/PhysRevLett.99.118301

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We investigate the competition between spinodal decomposition and dynamical arrest using aqueous solutions of the globular protein lysozyme as a model system for colloids with short-range attractions. We show that quenches below a temperature T-a lead to gel formation as a result of a local arrest of the protein-dense phase during spinodal decomposition. The rheological properties of these gels allow us to use centrifugation experiments to determine the local densities of both phases and to precisely locate the gel boundary and the attractive glass line close to and within the unstable region of the phase diagram.

引用

页数：4

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