Protein phosphorylation and dephosphorylation in physiologic and oncologic processes

被引：42

作者：

Patarca, R

机构：

[1] Univ Miami, Sch Med, Dept Med, EM Papper Lab Clin Immunol, Miami, FL 33160 USA

[2] Univ Miami, Sch Med, Dept Microbiol & Immunol, EM Papper Lab Clin Immunol, Miami, FL 33160 USA

来源：

CRITICAL REVIEWS IN ONCOGENESIS | 1996年 / 7卷 / 5-6期

关键词：

protein kinase; protein phosphatase; tyrosine; serine/threonine;

D O I：

10.1615/CritRevOncog.v7.i5-6.20

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Phosphorylation and dephosphorylation of proteins is an important regulatory mechanism of cell metabolism, proliferation and differentiation. The present review summarizes the known key players, their interactions, effects on physiological processes, and their role in pathology and neoplasia.

引用

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页码：343 / 432

页数：90

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