Role of Vitamin A in the Immune System

被引：343

作者：

Huang, Zhiyi ^{[1
,2
]}

Liu, Yu ^{[1
,2
]}

Qi, Guangying ^{[1
,2
]}

Brand, David ^{[3
]}

Zheng, Song Guo ^{[4
]}

机构：

[1] Guilin Med Univ, Dept Pathol & Physiopathol, Guilin 541004, Guangxi, Peoples R China

[2] Guilin Med Univ, Lab Tumor Immunol & Microenvironm Regulat, Guilin 541004, Guangxi, Peoples R China

[3] VA Med Ctr, Res Serv, Memphis, TN 38104 USA

[4] Penn State Univ, Milton S Hershey Med Ctr, Dept Med, Div Rheumatol, Hershey, PA 17033 USA

来源：

JOURNAL OF CLINICAL MEDICINE | 2018年 / 7卷 / 09期

关键词：

vitamin A; immunology; infectious disease; REGULATORY T-CELLS; TRANS-RETINOIC ACID; INNATE LYMPHOID-CELLS; TGF-BETA; B-CELLS; SMALL-INTESTINE; PULMONARY TUBERCULOSIS; TRANSCRIPTION FACTOR; PRESCHOOL-CHILDREN; HYPERVITAMINOSIS-A;

D O I：

10.3390/jcm7090258

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Vitamin A (VitA) is a micronutrient that is crucial for maintaining vision, promoting growth and development, and protecting epithelium and mucus integrity in the body. VitA is known as an anti-inflammation vitamin because of its critical role in enhancing immune function. VitA is involved in the development of the immune system and plays regulatory roles in cellular immune responses and humoral immune processes. VitA has demonstrated a therapeutic effect in the treatment of various infectious diseases. To better understand the relationship between nutrition and the immune system, the authors review recent literature about VitA in immunity research and briefly introduce the clinical application of VitA in the treatment of several infectious diseases.

引用

页数：16

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