Synthesis of ethylene isosteres of β-D-galactosyl- and β-D-glucosyl-L-asparagine

被引：23

作者：

Dondoni, A ^{[1
]}

Massi, A ^{[1
]}

Marra, A ^{[1
]}

机构：

[1] Univ Ferrara, Dipartimento Chim, Chim Organ Lab, I-44100 Ferrara, Italy

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 36期

关键词：

amino acids and derivatives; carbohydrates; enol ethers; Mukaiyama reactions;

D O I：

10.1016/S0040-4039(98)01376-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Mukaiyama-type coupling of galactosyl and glucosyl aldehydes with a four-carbon atom silyl enol ether carrying the oxazolidine ring affords the corresponding sugar containing aldols (65-74%) that upon deoxygenation and oxidative cleavage of the heterocyclic ring lead to the title carbon-linked beta-glycosyl amino acids. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：6601 / 6604

页数：4

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