From allylic alcohols to aldols via a novel, tandem isomerization-condensation catalyzed by Fe(CO)5

被引：57

作者：

Crévisy, C ^{[1
]}

Wietrich, M ^{[1
]}

Le Boulaire, V ^{[1
]}

Uma, R ^{[1
]}

Grée, R ^{[1
]}

机构：

[1] Ecole Natl Super Chim Rennes, CNRS, Lab Synth & Activat Biomol, F-35700 Rennes, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 03期

关键词：

aldols; catalysts; transition metals;

D O I：

10.1016/S0040-4039(00)02000-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Allylic alcohols react with aldehydes, in the presence of catalytic amounts of Fe(CO), and under irradiation, to give mainly aldol products. A small amount of ketone resulting from the classical isomerization process is also isolated. This new aldol-type reaction is a complete atom economy process occurring under neutral conditions. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：395 / 398

页数：4

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