Molecule-scale controlled-release system based on light-responsive silica nanoparticles

被引：52

作者：

Wu, Chuanliu

Chen Chen

Lai, Jinping

Chen, Jianbin

Mu, Xue

Zheng, Jinsheng

Zhao, Yibing ^{[1
]}

机构：

[1] Xiamen Univ, Dept Chem, Coll Chem & Chem Engn, Minist Educ, Xiamen 361005, Fujian, Peoples R China

[2] Xiamen Univ, Coll Chem & Chem Engn, Minist Educ, Key Lab Analyt Sci, Xiamen 361005, Fujian, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2008年 / 23期

关键词：

D O I：

10.1039/b804886j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a molecule-scale controlled-release system based on silica nanoparticles bearing a photoactive o-nitrobenzyl bromide linkage, which allows cage and release of drug or biologically active molecules by light.

引用

页码：2662 / 2664

页数：3

共 24 条

[1] Surface modification of silica nanoparticles to reduce aggregation and nonspecific binding [J].

Bagwe, RP ;

Hilliard, LR ;

Tan, WH .

LANGMUIR, 2006, 22 (09) :4357-4362

[2] Optimization of dye-doped silica nanoparticles prepared using a reverse microemulsion method [J].

Bagwe, RP ;

Yang, CY ;

Hilliard, LR ;

Tan, WH .

LANGMUIR, 2004, 20 (19) :8336-8342

[3] Photolabile protecting groups and linkers [J].

Bochet, CG .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 2002, (02) :125-142

[4] A cell nanoinjector based on carbon nanotubes [J].

Chen, Xing ;

Kis, Andras ;

Zettl, A. ;

Bertozzi, Carolyn R. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (20) :8218-8222

[5] Magnetic glyco-nanoparticles: A unique tool for rapid pathogen detection, decontamination, and strain differentiation [J].

El-Boubbou, Kheireddine ;

Gruden, Cyndee ;

Huang, Xuefei .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (44) :13392-+

[6] Light-regulated release of DNA and its delivery to nuclei by means of photolabile gold nanoparticles [J].

Han, Gang ;

You, Chang-Cheng ;

Kim, Byoung-Jin ;

Turingan, Rosemary S. ;

Forbes, Neil S. ;

Martin, Craig T. ;

Rotello, Vincent M. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (19) :3165-3169

[7] Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing [J].

Kam, NWS ;

Liu, Z ;

Dai, HJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (36) :12492-12493

[8] Ultrasound-triggered smart drug release from a poly(dimethylsiloxane)-mesoporous silica composite [J].

Kim, Hyun-Jong ;

Matsuda, Hirofumi ;

Zhou, Haoshen ;

Honma, Itaru .

ADVANCED MATERIALS, 2006, 18 (23) :3083-+

[9] ELECTRICALLY ERODIBLE POLYMER GEL FOR CONTROLLED RELEASE OF DRUGS [J].

KWON, IC ;

BAE, YH ;

KIM, SW .

NATURE, 1991, 354 (6351) :291-293

[10] On-off transport through a thermoresponsive hydrogel composite membrane [J].

Li, SK ;

D'Emanuele, A .

JOURNAL OF CONTROLLED RELEASE, 2001, 75 (1-2) :55-67

← 1 2 3 →