Rapid and efficient identification of bacteria using gold-nanoparticle -: Poly(para-phenyleneethynylene) constructs

被引:338
作者
Phillips, Ronnie L. [1 ]
Miranda, Oscar R. [2 ]
You, Chang-Cheng [2 ]
Rotello, Vincent M. [2 ]
Bunz, Uwe H. F. [1 ]
机构
[1] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA
[2] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA
关键词
bacteria; bioanalysis; biosensors; conjugated polymers; gold nanoparticles;
D O I
10.1002/anie.200703369
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Microbiological intelligence: Simple constructs of hydrophobically functionalized gold nanoarticles and a conjugated polymer (poly(para- phenyleneethynylene, PPE) are able to identify three different strains of E. coli in minutes. The negatively charged bacteria replace the negatively charged conjugated polymers from the positively charged gold nanoparticles (see scheme), differentially restoring the polymer fluorescence. (Figure Presented) © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:2590 / 2594
页数:5
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