MTERF1 Gives mtDNA an Unusual Twist

被引:7
作者
Gustafsson, Claes M. [1 ]
Larsson, Nils-Goran [2 ]
机构
[1] Univ Gothenburg, Dept Biochem & Cell Biol, S-40530 Gothenburg, Sweden
[2] Max Planck Inst Biol Ageing, D-50931 Cologne, Germany
关键词
TERMINATION FACTOR MTERF; MITOCHONDRIAL TRANSCRIPTION; PROTEIN; DNA;
D O I
10.1016/j.cmet.2010.06.006
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Expression of mtDNA is critical for biogenesis of the oxidative phosphorylation system, but the regulatory processes are poorly understood. Recent work in Cell (Yakubovskaya et al., 2010) reports a novel DNA-binding fold in mitochondrial transcription termination factor 1 (MTERF1), which causes unwinding and base eversion at its target mtDNA sequence.
引用
收藏
页码:3 / 4
页数:2
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