The ligand gated ion channel database

被引：74

作者：

Le Novère, N ^{[1
]}

Changeux, JP ^{[1
]}

机构：

[1] Inst Pasteur, CNRS, URA 1281, F-75724 Paris 15, France

来源：

NUCLEIC ACIDS RESEARCH | 1999年 / 27卷 / 01期

关键词：

D O I：

10.1093/nar/27.1.340

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The ligand gated ion channels (LGICs) are ionotropic receptors to neurotransmitters. Their physiological effect is carried out by the opening of an ionic channel upon binding of a particular neurotransmitter. These LGICs constitute superfamilies of receptors formed by homologous subunits. A database has been developed to handle the growing wealth of cloned subunits, This database contains nucleic acid sequences, protein sequences, as well as multiple sequence alignments and phylogenetic studies. This database is accessible via the worldwide web (http://www. pasteur.fr/units/neubiomol/LGIC.html), where it is continuously updated. A downloadable version is also available [currently v0.1 (98.06)].

引用

页码：340 / 342

页数：3

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