Inducible nitric oxide synthase and Salmonella infection

被引:34
作者
Cherayil, BJ
Antos, D
机构
[1] Massachusetts Gen Hosp, Combined Program Pediat Gastroenterol & Nutr, Mucosal Immun Lab, Boston, MA 02129 USA
[2] Harvard Univ, Sch Med, Boston, MA 02129 USA
关键词
Salmonella; nitric oxide; immunity;
D O I
10.1016/S1286-4579(01)01428-9
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Salmonella infection is associated with the increased expression of inducible nitric oxide synthase in macrophages and other cells. This review summarizes current knowledge of the molecular mechanisms involved in the induction process, and discusses the functional significance of nitric oxide production in the context of host defense against Salmonella. (C) 2001 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:771 / 776
页数:6
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