Identification of SopE2, a Salmonella secreted protein which is highly homologous to SopE and involved in bacterial invasion of epithelial cells

被引：131

作者：

Bakshi, CS

Singh, VP

Wood, MW

Jones, PW

Wallis, TS

Galyov, EE ^{[1
]}

机构：

[1] Inst Anim Hlth, Compton RG20 7NN, Berks, England

[2] Indian Vet Res Inst, Izatnagar 243122, Uttar Pradesh, India

来源：

JOURNAL OF BACTERIOLOGY | 2000年 / 182卷 / 08期

关键词：

D O I：

10.1128/JB.182.8.2341-2344.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

Type III secreted Sop protein effecters are delivered into target eukaryotic cells and elicit cellular responses underlying Salmonella pathogenicity. In this work we have identified another secreted protein, SopE2, and showed that SopE2 is an important invasion-associated effector. SopE2 is encoded by the sopE2 gene which is present and conserved in pathogenic strains of Salmonella. SopE2 is highly homologous to SopE, a protein encoded by a gene within a temperate bacteriophage and present in only some pathogenic strains.

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页码：2341 / 2344

页数：4

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