Development and Applications of Fluorogenic Probes for Mercury(II) Based on Vinyl Ether Oxymercuration

被引：160

作者：

Ando, Shin ^{[1
]}

Koide, Kazunori ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 08期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

WASTE-WATER; METHYLMERCURY EXPOSURE; FLUORESCENT SENSOR; FISH CONSUMPTION; PROTECTING GROUP; ALLYL ETHER; TURN-ON; HG2+; ION; CHEMODOSIMETER;

D O I：

10.1021/ja108028m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Mercury is a major threat to the environment and to human health. It is highly desirable to develop a user-friendly kit for on-site mercury detection. Such a method must be able to detect mercury below the threshold levels for drinking water, 1-2 ppb. We developed a fluorescence method based on the oxymercuration of vinyl ethers to detect mercury in dental and environmental samples. Chloride ions interfered with the oxymercuration reaction, but the addition of AgNO3 solved this problem. Fine electronic and structural tuning led to the development of a more responsive probe that was less sensitive to chloride ion interference. This second-generation probe could detect 1 ppb mercury ions in water.

引用

页码：2556 / 2566

页数：11

共 67 条

[1] BOND ENERGIES OF TRANSITION METAL HALIDES [J].