Synthesis of spongian diterpenes:: (-)-spongian-16-oxo-17-al and (-)-acetyldendrillol-1

被引：11

作者：

Arnó, M ^{[1
]}

González, MA ^{[1
]}

Marín, ML ^{[1
]}

Zaragozá, RJ ^{[1
]}

机构：

[1] Univ Valencia, Dept Quim Organ, E-46100 Burjassot, Spain

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 09期

关键词：

diterpenes; marine metabolites; sponges; synthesis; podocarpenone;

D O I：

10.1016/S0040-4039(00)02339-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient diastereoselective synthesis of the spongian diterpenes (-)-spongian-16-oxo-17-al (1) and (-)-acetyldendrillol-1 (13) is described starting from (+)-podocarp-8(14)-13-one (6) via the ester-dialdehyde 11 as key intermediate. The absolute configuration at C-17 in synthetic compound 13 has conclusively been proved by NOE experiments. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1669 / 1671

页数：3

共 21 条

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