A new toxic alkylpyrrolidine alkaloid from Arisarum vulgare

被引：14

作者：

Melhaoui, A ^{[1
]}

机构：

[1] Univ Mohamed 1er, Fac Sci, Lab Phytochim & Pharmacognosie, Oujda 60000, Morocco

来源：

PLANTA MEDICA | 1998年 / 64卷 / 05期

关键词：

D O I：

10.1055/s-2006-957490

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

From the tubers of Arisarum vulgare Targ. (Araceae), a new toxic alkylpyrrolidine alkaloid has been purified and characterized. By 2D COSY NMR spectroscopic methods, its structure was elucidated as: (-)-R-N-methyl-2-[9'-(2 "-methoxyphenyl)nonyl]pyrrolidine.

引用

页码：476 / 477

页数：2

共 7 条

[1] ASYMMETRIC-SYNTHESIS .13. SYNTHESIS OF 2-ALKYLPYRROLIDINES - TOWARDS AZABICYCLIC SYSTEMS [J].

ARSENIYADIS, S ;

HUANG, PQ ;

HUSSON, HP .

TETRAHEDRON LETTERS, 1988, 29 (06) :631-634

[2] Enantioselective total synthesis of irniine and bgugaine, bioactive 2-alkylpyrrolidine alkaloids [J].

Jossang, A ;

Melhaoui, A ;

Bodo, B .

HETEROCYCLES, 1996, 43 (04) :755-766

[3]

MELHAOUI A, 1995, NAT PROD LETT, V7, P101, DOI 10.1080/10575639508043196

[4] STRUCTURE OF IRNIINE, A PYRROLIDINE ALKALOID FROM ARISARUM-VULGARE [J].

MELHAOUI, A ;

JOSSANG, A ;

BODO, B .

JOURNAL OF NATURAL PRODUCTS, 1992, 55 (07) :950-952

[5]

Melhaoui A., 1993, NAT PROD LETT, V2, P237

[6] BRINE SHRIMP - A CONVENIENT GENERAL BIOASSAY FOR ACTIVE-PLANT CONSTITUENTS [J].

MEYER, BN ;

FERRIGNI, NR ;

PUTNAM, JE ;

JACOBSEN, LB ;

NICHOLS, DE ;

MCLAUGHLIN, JL .

PLANTA MEDICA, 1982, 45 (01) :31-34

[7] HIGHLY STEREOSELECTIVE ADDITION OF ALKYLCOPPER REAGENTS TO N-ACYLIMINIUM IONS - ENANTIOSELECTIVE SYNTHESIS OF TRANS-2-BUTYL-5-HEPTYLPYRROLIDINE [J].

SKRINJAR, M ;

WISTRAND, LG .

TETRAHEDRON LETTERS, 1990, 31 (12) :1775-1778

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