Optimization of temperature and initial pH and kinetic analysis of tartaric acid production by Gluconobacter suboxydans

被引:16
作者
Chandrashekar, K [1 ]
Felse, PA [1 ]
Panda, T [1 ]
机构
[1] Indian Inst Technol, Dept Chem Engn, Biotechnol Res Ctr, Madras 600036, Chennai, India
关键词
D O I
10.1007/PL00009044
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Response surface methodology was applied for the simultaneous optimization of initial pH and temperature of fermentation for the production of tartaric acid by Gluconobacter suboxydans. A temperature of 32.8 degrees C and an initial pH of 6.05 was found to be most suitable. Kinetic analysis for the growth of Gluconobacter suboxydans and product formation was done and a logistic model was used to describe the growth of Gluconobacter suboxydans while the Leudeking-Piret model explained the product formation. Parameters of the model were evaluated and tartaric acid formation was found to be non-growth associated.
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页码:203 / 207
页数:5
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