Dual-axes confocal microscopy with post-objective scanning and low-coherence heterodyne detection

被引：49

作者：

Wang, TD ^{[1
]}

Contag, CH

Mandella, MJ

Chan, NY

Kino, GS

机构：

[1] Stanford Univ, Sch Med, Stanford, CA 94305 USA

[2] Opt Biopsy Technol Inc, Palo Alto, CA 94301 USA

[3] Stanford Univ, Edward L Ginzton Lab, Stanford, CA 94305 USA

来源：

OPTICS LETTERS | 2003年 / 28卷 / 20期

关键词：

D O I：

10.1364/OL.28.001915

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We present a dual-axes confocal microscope that employs postobjective scanning and low-coherence heterodyne detection to collect vertical cross-sectional images from biological tissue with high axial resolution, reduced noise from scattered light, deep tissue penetration, and a large dynamic range. This architecture can be scaled down to millimeter dimensions with microelectromechanical systems technology for performance of in vivo optical biopsy. (C) 2003 Optical Society of America.

引用

页码：1915 / 1917

页数：3

共 5 条

[1]

CRAWFORD JM, 1999, ROBBINS PATHOLOGIC B, P781

[2] Speckle reduction in optical coherence tomography by "path length encoded" angular compounding [J].