共 11 条
Speckle reduction in optical coherence tomography by "path length encoded" angular compounding
被引:136
作者:

Iftimia, N
论文数: 0 引用数: 0
h-index: 0
机构: Harvard Univ, Sch Med, Boston, MA 02114 USA

Bouma, BE
论文数: 0 引用数: 0
h-index: 0
机构: Harvard Univ, Sch Med, Boston, MA 02114 USA

Tearney, GJ
论文数: 0 引用数: 0
h-index: 0
机构: Harvard Univ, Sch Med, Boston, MA 02114 USA
机构:
[1] Harvard Univ, Sch Med, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Wellman Labs Photomed, Dept Pathol, Boston, MA 02114 USA
关键词:
speckle reduction;
optical coherence tomography;
catheters;
endoscopes;
D O I:
10.1117/1.1559060
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
Speckle, the dominant factor reducing image quality in optical coherence tomography (OCT), limits the ability to identify cellular structures that are essential for diagnosis of a variety of diseases. We describe a new high-speed method for implementing angular compounding by path length encoding (ACPE) for reducing speckle in OCT images. By averaging images obtained at different incident angles, with each image encoded by path length, ACPE maintains high-speed image acquisition and requires minimal modifications to OCT probe optics. ACPE images obtained from tissue phantoms and human skin in vivo demonstrate a qualitative improvement over traditional OCT and an increased SNR that correlates well with theory. (C) 2003 Society of Photo-Optical Instrumentation Engineers.
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页码:260 / 263
页数:4
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