Roles of PDGF in animal development

被引：437

作者：

Hoch, RV

Soriano, P

机构：

[1] Fred Hutchinson Canc Res Ctr, Program Dev Biol, Seattle, WA 98109 USA

[2] Fred Hutchinson Canc Res Ctr, Div Basic Sci, Seattle, WA 98109 USA

来源：

DEVELOPMENT | 2003年 / 130卷 / 20期

关键词：

GROWTH-FACTOR RECEPTOR; FACTOR-ALPHA-RECEPTOR; SMOOTH-MUSCLE-CELLS; NEURAL CREST CELLS; ZEBRAFISH EMBRYONIC-DEVELOPMENT; PROTEASE-ACTIVATED LIGAND; CENTRAL-NERVOUS-SYSTEM; SIMIAN SARCOMA-VIRUS; FACTOR-A-CHAIN; IN-VIVO;

D O I：

10.1242/dev.00721

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Recent advances in genetic manipulation have greatly expanded our understanding of cellular responses to platelet-derived growth factors (PDGFs) during animal development. In addition to driving mesenchymal proliferation, PDGFs have been shown to direct the migration, differentiation and function of a variety of specialized mesenchymal and migratory cell types, both during development and in the adult animal. Furthermore, the availability of genomic sequence data has facilitated the identification of novel PDGF and PDGF receptor (PDGFR) family members in C elegans, Drosophila, Xenopus, zebrafish and mouse. Early data from these different systems suggest that some functions of PDGFs have been evolutionarily conserved.

引用

页码：4769 / 4784

页数：16

共 115 条

[1] Expression analysis of PDGF-C in adult and developing mouse tissues
Aase, K
Abramsson, A
Karlsson, L
Betsholtz, C
Eriksson, U
[J]. MECHANISMS OF DEVELOPMENT, 2002, 110 (1-2) : 187 - 191
[2] Andrews A, 1999, INVEST OPHTH VIS SCI, V40, P2683
[3] Platelet-derived growth factor receptor β regulates migration and DNA synthesis in metanephric mesenchymal cells
Arar, M
Xu, YC
Elshihabi, I
Barnes, JL
Choudhury, GG
Abboud, HE
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (13) : 9527 - 9533
[4] Platelet-derived growth factor A modulates limb chondrogenesis both in vivo and in vitro
Ataliotis, P
[J]. MECHANISMS OF DEVELOPMENT, 2000, 94 (1-2) : 13 - 24
[5] ATALIOTIS P, 1995, DEVELOPMENT, V121, P3099
[6] NUCLEOTIDE-SEQUENCE OF A CDNA CLONE OF XENOPUS PLATELET-DERIVED GROWTH FACTOR-A-CHAIN
BEJCEK, BE
LI, DY
DEUEL, TF
[J]. NUCLEIC ACIDS RESEARCH, 1990, 18 (03) : 680 - 680
[7] Benjamin LE, 1998, DEVELOPMENT, V125, P1591
[8] PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor
Bergsten, E
Uutela, M
Li, XR
Pietras, K
Östman, A
Heldin, CH
Alitalo, K
Eriksson, U
[J]. NATURE CELL BIOLOGY, 2001, 3 (05) : 512 - 516
[9] Developmental roles of platelet-derived growth factors
Betsholtz, C
Karlsson, L
Lindahl, P
[J]. BIOESSAYS, 2001, 23 (06) : 494 - 507
[10] COMPLEMENT COMPONENTS CLR/CLS, BONE MORPHOGENIC PROTEIN-1 AND XENOPUS-LAEVIS DEVELOPMENTALLY REGULATED PROTEIN UVS.2 SHARE COMMON REPEATS
BORK, P
[J]. FEBS LETTERS, 1991, 282 (01) : 9 - 12

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