Viroid trafficking: a small RNA makes a big move

被引:37
作者
Ding, B
Itaya, A
Zhong, XH
机构
[1] Ohio State Univ, Dept Plant Cellular & Mol Biol, Columbus, OH 43210 USA
[2] Ohio State Univ, Ctr Plant Biotechnol, Columbus, OH 43210 USA
基金
美国国家科学基金会;
关键词
D O I
10.1016/j.pbi.2005.09.001
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
RNA trafficking has broad implications in the systemic spread of infectious agents, plant defense, and the systemic regulation of gene expression. The mechanisms that regulate trafficking remain poorly understood. The non-coding, infectious viroid RNAs are emerging as highly tractable model systems for the investigation of the basic mechanisms of RNA trafficking. Recent studies on viroids have led to new insights into the direct role of RNAs in intracellular and systemic trafficking, and to the identification of cellular proteins that might play a role in RNA trafficking. Here, we discuss these areas of progress, emphasizing on the unifying principles that control the trafficking of viroid, viral and endogenous RNAs.
引用
收藏
页码:606 / 612
页数:7
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