Role of lycopene as antioxidant carotenoid in the prevention of chronic diseases: A review

被引：488

作者：

Rao, AV ^{[1
]}

Agarwal, S ^{[1
]}

机构：

[1] Univ Toronto, Fac Med, Dept Nutr Sci, Toronto, ON M5S 3E2, Canada

来源：

NUTRITION RESEARCH | 1999年 / 19卷 / 02期

关键词：

lycopene; carotenoids; oxidative stress; antioxidant; chronic diseases;

D O I：

10.1016/S0271-5317(98)00193-6

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Lycopene is a naturally present carotenoid in tomatoes. Among the carotenoids, lycopene is a major component found in the serum. High levels of lycopene have also been found in the testes, adrenal glands, prostate. Several recent studies including cell culture, animal and epidemiological investigations have indicated the effect of dietary lycopene in reducing the risk of chronic diseases such as cancer and coronary heart disease. Although, the antioxidant properties of lycopene are thought to be primarily responsible for its beneficial properties, evidence is accumulating to suggest other mechanisms such as intercellular gap junction communication, hormonal and immune system modulation and metabolic pathways may also be involved. This review summarizes the background information about lycopene and presents the most current knowledge with respect to its role in human health. (C) 1999 Elsevier Science Inc.

引用

页码：305 / 323

页数：19

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