Berberine and coptisine free bases

被引：32

作者：

Dostál, J

Man, S

Seckárová, P

Hulová, D

Necas, M

Potáek, M

Tousek, J

Dommisse, R

Van Dongen, W

Marek, R

机构：

[1] Masaryk Univ, Fac Med, Dept Biochem, CZ-66243 Brno, Czech Republic

[2] Masaryk Univ, Fac Sci, Dept Organ Chem, CZ-61137 Brno, Czech Republic

[3] Masaryk Univ, Fac Sci, Natl Ctr Biomol Res, CZ-61137 Brno, Czech Republic

[4] Masaryk Univ, Fac Sci, Dept Inorgan Chem, CZ-61137 Brno, Czech Republic

[5] Masaryk Univ, Fac Sci, Dept Theoret & Phys Chem, CZ-61137 Brno, Czech Republic

[6] Univ Antwerp, Dept Chem, B-2020 Antwerp, Belgium

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2004年 / 687卷 / 1-3期

关键词：

berberine; coptisine; protoberberine alkaloids; NMR spectroscopy; X-ray crystallography;

D O I：

10.1016/j.molstruc.2003.09.018

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 [物理化学]; 081704 [应用化学];

摘要：

The free bases of protoberberine alkaloids berberine and coptisine and related compounds have been examined. The H-1 and C-13 NMR data of 8-hydroxy-7,8-dihydroberberine (2a), 8-hydroxy-7,8-dihydrocoptisine (2b), bis(7,8-dihydroberberin-8-yl) ether (3a), 8-oxoberberine (5a), and 8-oxocoptisine (5b) as well as X-ray data of compounds 2a, 5a, and 5b are reported and discussed. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：135 / 142

页数：8

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