Demethylation of 2,4-dimethoxyquinolines: the synthesis of atanine

被引：30

作者：

Jones, K

Roset, X

Rossiter, S

Whitfield, P

机构：

[1] Kings Coll London, Dept Chem, London WC2R 2LS, England

[2] Kings Coll London, Sch Life Sci, London SE1 9NN, England

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2003年 / 1卷 / 24期

关键词：

D O I：

10.1039/b311281k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the quinoline alkaloid atanine 6, by selective demethylation of the 2,4-dimethoxyquinoline 11 is presented. An alternative demethylation utilising a thiolate anion leads to the regioisomeric 4-hydroxyquinoline 13.

引用

页码：4380 / 4383

页数：4

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