共 49 条
Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial
被引:71
作者:
Belski, R.
[1
,2
]
Mori, T. A.
[1
,2
]
Puddey, I. B.
[1
,2
]
Sipsas, S.
Woodman, R. J.
[3
]
Ackland, T. R.
[4
]
Beilin, L. J.
[1
,2
]
Dove, E. R.
[1
,2
]
Carlyon, N. B.
[1
,2
]
Jayaseena, V.
[2
,5
]
Hodgson, J. M.
[1
,2
]
机构:
[1] Univ Western Australia, Sch Med & Pharmacol, Perth, WA 6009, Australia
[2] Western Australian Inst Med Res, Ctr Food & Genom Med, Perth, WA, Australia
[3] Flinders Univ S Australia, Sch Med, Adelaide, SA 5001, Australia
[4] Univ Western Australia, Sch Sport Sci Exercise & Hlth, Perth, WA 6009, Australia
[5] Curtin Univ, Sch Publ Hlth, Curtin Hlth Innovat Res Ctr, Perth, WA, Australia
关键词:
lupin;
weight loss;
blood pressure;
insulin;
lipids;
DENSITY-LIPOPROTEIN CHOLESTEROL;
DIETARY-PROTEIN INTAKE;
BLOOD-PRESSURE;
INSULIN-RESISTANCE;
FIBER INTAKE;
CARBOHYDRATE INTAKE;
GLUCOSE-METABOLISM;
GLYCEMIC INDEX;
KERNEL FIBER;
SATIETY;
D O I:
10.1038/ijo.2010.213
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Background: Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre. Objective: To investigate the effects of a lupin-enriched diet, during and following energy restriction, on body weight and composition and cardiovascular disease risk factors in overweight individuals. Design: Participants (n = 131) were recruited to a 12-month parallel-design trial. They were randomly assigned to consume lupin-enriched foods or matching high-carbohydrate control foods. All participants underwent 3 months of weight loss, 1 month of weight stabilization and 8 months of weight maintenance. Body weight and composition and cardiovascular disease risk factors were assessed at baseline, 4 and 12 months. Results: Lupin, relative to control, did not significantly influence (mean difference (95% CI)) weight loss at 4 months (0.1 kg (-1.2, 1.4)) and 12 months (-0.6 kg (-2.0, 0.8)), maintenance of weight loss from 4 to 12 months (-0.7 kg (-1.83, 0.48)) or measures of body fat and fat-free mass. Relative to control, 24-h ambulatory systolic (-1.3mmHg (-2.4, -0.3), P = 0.016) and diastolic (-1.0mmHg (-1.9, -0.2), P = 0.021) blood pressures were lower at 12 months but not at 4 months; fasting insulin concentrations and homeostasis model assessment (HOMA) scores were significantly lower at 4 months (-1.2mUl(-1) (-1.3, -1.1), P = 0.004 and -0.6 units (-1.0, -0.19), P = 0.004) and 12 months (-1.3 mUl(-1) (-1.4, -1.1), P < 0.001 and -0.7 units (-1.1, -0.24), P = 0.002). Conclusions: A diet higher in protein and fibre derived from lupin-enriched foods does not enhance weight loss or improve the maintenance of weight loss. However, such a diet may provide cardiovascular health benefits in terms of insulin sensitivity and blood pressure. International Journal of Obesity (2011) 35, 810-819; doi:10.1038/ijo.2010.213; published online 12 October 2010
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页码:810 / 819
页数:10
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