Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial

被引：71

作者：

Belski, R. ^{[1
,2
]}

Mori, T. A. ^{[1
,2
]}

Puddey, I. B. ^{[1
,2
]}

Sipsas, S.

Woodman, R. J. ^{[3
]}

Ackland, T. R. ^{[4
]}

Beilin, L. J. ^{[1
,2
]}

Dove, E. R. ^{[1
,2
]}

Carlyon, N. B. ^{[1
,2
]}

Jayaseena, V. ^{[2
,5
]}

Hodgson, J. M. ^{[1
,2
]}

机构：

[1] Univ Western Australia, Sch Med & Pharmacol, Perth, WA 6009, Australia

[2] Western Australian Inst Med Res, Ctr Food & Genom Med, Perth, WA, Australia

[3] Flinders Univ S Australia, Sch Med, Adelaide, SA 5001, Australia

[4] Univ Western Australia, Sch Sport Sci Exercise & Hlth, Perth, WA 6009, Australia

[5] Curtin Univ, Sch Publ Hlth, Curtin Hlth Innovat Res Ctr, Perth, WA, Australia

来源：

INTERNATIONAL JOURNAL OF OBESITY | 2011年 / 35卷 / 06期

关键词：

lupin; weight loss; blood pressure; insulin; lipids; DENSITY-LIPOPROTEIN CHOLESTEROL; DIETARY-PROTEIN INTAKE; BLOOD-PRESSURE; INSULIN-RESISTANCE; FIBER INTAKE; CARBOHYDRATE INTAKE; GLUCOSE-METABOLISM; GLYCEMIC INDEX; KERNEL FIBER; SATIETY;

D O I：

10.1038/ijo.2010.213

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre. Objective: To investigate the effects of a lupin-enriched diet, during and following energy restriction, on body weight and composition and cardiovascular disease risk factors in overweight individuals. Design: Participants (n = 131) were recruited to a 12-month parallel-design trial. They were randomly assigned to consume lupin-enriched foods or matching high-carbohydrate control foods. All participants underwent 3 months of weight loss, 1 month of weight stabilization and 8 months of weight maintenance. Body weight and composition and cardiovascular disease risk factors were assessed at baseline, 4 and 12 months. Results: Lupin, relative to control, did not significantly influence (mean difference (95% CI)) weight loss at 4 months (0.1 kg (-1.2, 1.4)) and 12 months (-0.6 kg (-2.0, 0.8)), maintenance of weight loss from 4 to 12 months (-0.7 kg (-1.83, 0.48)) or measures of body fat and fat-free mass. Relative to control, 24-h ambulatory systolic (-1.3mmHg (-2.4, -0.3), P = 0.016) and diastolic (-1.0mmHg (-1.9, -0.2), P = 0.021) blood pressures were lower at 12 months but not at 4 months; fasting insulin concentrations and homeostasis model assessment (HOMA) scores were significantly lower at 4 months (-1.2mUl(-1) (-1.3, -1.1), P = 0.004 and -0.6 units (-1.0, -0.19), P = 0.004) and 12 months (-1.3 mUl(-1) (-1.4, -1.1), P < 0.001 and -0.7 units (-1.1, -0.24), P = 0.002). Conclusions: A diet higher in protein and fibre derived from lupin-enriched foods does not enhance weight loss or improve the maintenance of weight loss. However, such a diet may provide cardiovascular health benefits in terms of insulin sensitivity and blood pressure. International Journal of Obesity (2011) 35, 810-819; doi:10.1038/ijo.2010.213; published online 12 October 2010

引用

页码：810 / 819

页数：10

共 49 条

[41] PHYSICAL-ACTIVITY ASSESSMENT METHODOLOGY IN THE 5-CITY PROJECT [J].