The role of nucleotide sugar transporters in development of eukaryotes

被引：46

作者：

Liu, Li ^{[1
]}

Xu, Yu-Xin ^{[1
]}

Hirschberg, Carlos B. ^{[1
]}

机构：

[1] Boston Univ, Goldman Sch Dent Med, Dept Mol & Cell Biol, Boston, MA 02118 USA

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2010年 / 21卷 / 06期

基金：

美国国家卫生研究院;

关键词：

Golgi apparatus; Nucleotide sugar transporter; Glycosylation; Development; Diseases; GDP-FUCOSE TRANSPORTER; ELEGANS VULVAL MORPHOGENESIS; UDP-N-ACETYLGLUCOSAMINE; DEFICIENCY TYPE-II; CAENORHABDITIS-ELEGANS; GOLGI-APPARATUS; MANNOSE TRANSPORTERS; CONGENITAL DISORDER; ENDOPLASMIC-RETICULUM; HEPARAN-SULFATE;

D O I：

10.1016/j.semcdb.2010.02.002

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The Golgi apparatus membrane of all eukaryotes has nucleotide sugar transporters which play essential roles in the glycosylation of glycoproteins, proteoglycans and glycolipids. Mutations of these transporters have broad developmental phenotypes across many species including diseases in humans and cattle. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：600 / 608

页数：9

共 62 条

[1] A mutant yeast deficient in golgi transport of uridine diphosphate N-acetylglucosamine [J].

Abeijon, C ;

Mandon, EC ;

Robbins, PW ;

Hirschberg, CB .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (15) :8851-8854

[2] Complex vertebral malformation in Holstein calves [J].

Agerholm, JS ;

Bendixen, C ;

Andersen, O ;

Arnbjerg, J .

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 2001, 13 (04) :283-289

[3] SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-galactose [J].

Berninsone, P ;

Hwang, HY ;

Zemtseva, I ;

Horvitz, HR ;

Hirschberg, CB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (07) :3738-3743

[4] Golgi and endoplasmic reticulum functions take place in different subcellular compartments of Entamoeba histolytica [J].

Bredeston, LM ;

Caffaro, CE ;

Samuelson, J ;

Hirschberg, CB .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (37) :32168-32176

[5] sqv-3 -7, and -8, a set of genes affecting morphogenesis in Caenorhabditis elegans, encode enzymes required for glycosaminoglycan biosynthesis [J].

Bulik, DA ;

Wei, G ;

Toyoda, H ;

Kinoshita-Toyoda, A ;

Waldrip, WR ;

Esko, JD ;

Robbins, PW ;

Selleck, SB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (20) :10838-10843

[6] A single Caenorhabditis elegans golgi apparatus-type transporter of UDP-glucose, UDP-galactose, UDP-N-acetylglucosamine, and UDP-N-acetylgalactosamine [J].

Caffaro, Carolina E. ;

Luhn, Kerstin ;

Bakker, Hans ;

Vestweber, Dietmar ;

Samuelson, John ;

Berninsone, Patricia ;

Hirschberg, Carlos B. .

BIOCHEMISTRY, 2008, 47 (14) :4337-4344

[7] Functional redundancy between two Caenorhabditis elegans nucleotide sugar transporters with a novel transport mechanism [J].

Caffaro, Carolina E. ;

Hirschberg, Carlos B. ;

Berninsone, Patricia M. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (38) :27970-27975

[8] Nucleotide sugar transporters of the golgi apparatus: From basic science to diseases [J].

Caffaro, Carolina E. ;

Hirschberg, Carlos B. .

ACCOUNTS OF CHEMICAL RESEARCH, 2006, 39 (11) :805-812

[9] Independent and simultaneous translocation of two substrates by a nucleotide sugar transporter [J].

Caffaro, Carolina E. ;

Hirschberg, Carlos B. ;

Berninsone, Patricia M. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (44) :16176-16181

[10] Comparisons of mutants lacking the golgi UDP-Galactose or GDP-Mannose transporters establish that phosphoglycans are important for promastigote but not amastigote virulence in Leishmania major [J].

Capul, Althea A. ;

Hickerson, Suzanne ;

Barron, Tamara ;

Turco, Salvatore J. ;

Beverley, Stephen M. .

INFECTION AND IMMUNITY, 2007, 75 (09) :4629-4637

← 1 2 3 4 5 6 7 →