Is Repeat PCR Needed for Diagnosis of Clostridium difficile Infection?

被引：51

作者：

Luo, Robert F. ^{[1
]}

Banaei, Niaz ^{[1
,2
,3
]}

机构：

[1] Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA

[2] Stanford Univ, Sch Med, Dept Med Infect Dis, Stanford, CA 94305 USA

[3] Stanford Hosp & Clin, Clin Microbiol Lab, Palo Alto, CA 94304 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2010年 / 48卷 / 10期

关键词：

REAL-TIME PCR; IMMUNOASSAYS; DIARRHEA; CULTURE;

D O I：

10.1128/JCM.00722-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Patients with diarrhea, defined as loose or watery stool, and two or more Clostridium difficile tcdB PCR tests within 14 days of each other were investigated. Repeat PCR for 293 patients with a prior negative result yielded negative results in 396 (97.5%) of 406 tests. Ten new positives were detected, including one false positive. Repeat PCR within 7 days appears rarely useful, except for patients with evidence of a new infection.

引用

页码：3738 / 3741

页数：4

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