Enantio- and chemoselective bioreduction of β-keto nitriles by the fungus Curvularia lunata

被引：44

作者：

Dehli, JR ^{[1
]}

Gotor, V ^{[1
]}

机构：

[1] Univ Oviedo, Dept Quim Organ & Inorgan, E-33071 Oviedo, Spain

来源：

TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 18期

关键词：

D O I：

10.1016/S0957-4166(00)00348-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The use of methanol as cosolvent allows the chemoselective reduction of aromatic beta -keto nitriles by the fungus Curvularia lunata CECT 2130, yielding the corresponding (S)-beta -hydroxy nitriles in a highly enantioselective way. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3693 / 3700

页数：8

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