Control of Candida albicans murine vaginitis by topical administration of polycarbophil-econazole complex

被引：17

作者：

Ghelardi, E

Tavanti, A

Lupetti, A

Celandroni, F

Boldrini, E

Campa, M

Senesi, S

机构：

[1] Univ Pisa, Dipartimento Biomed Sperimentale Infett & Pubbl, I-56127 Pisa, Italy

[2] Farmigea SPA, I-56127 Pisa, Italy

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1998年 / 42卷 / 09期

关键词：

D O I：

10.1128/AAC.42.9.2434

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The complexation of econazole with the mucoadhesive polycarbophil was found to significantly improve the therapeutic benefit of the drug in the topical treatment of experimental vaginal candidiasis in mice, while no difference in the antimycotic activity exerted by econazole and polycarbophil econazole could be detected in vitro.

引用

收藏

页码：2434 / 2436

页数：3

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