Atopic dermatitis: An update and review of the literature

被引:42
作者
Lipozencic, Jasna
Wolf, Ronni
机构
[1] Zagreb Univ Hosp Ctr, Univ Dept Dermatol & Venereol, Zagreb 10000, Croatia
[2] Univ Zagreb, Sch Med, Zagreb 10000, Croatia
[3] Hebrew Univ Jerusalem, Hadassah Med Sch, IL-91010 Jerusalem, Israel
[4] Kaplan Med Ctr, Dermatol Unit, IL-76100 Rehovot, Israel
关键词
D O I
10.1016/j.det.2007.06.009
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 [皮肤病与性病学];
摘要
Atopic eczema/dermatitis from the aspects of immunologic background, genetics, skin barrier dysfunction, IgE receptors, and triggers of AD (including allergens, microorganisms, and autoantigens) is described. Also reviewed are diagnostic procedures, treatment modalities with topical treatment (emollients, topical corticosteroids, topical calcineurin inhibitors, wet wrap therapy, and topical antimicrobial therapy), systemic management (antimicrobials, systemic corticosteroids, cyclosporine A, azathioprine, antihistamines), and phototherapy. Primary and secondary prevention are discussed and the role of the different cell receptors and their up-and down-regulation in this setting are emphasized.
引用
收藏
页码:605 / +
页数:9
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