Curcumin and catechin co-loaded water-in-oil-in-water emulsion and its beverage application

被引:96
作者
Aditya, N. P. [1 ]
Aditya, Sheetal [1 ]
Yang, Han-Joo [1 ]
Kim, Hye Won [1 ]
Park, Sung Ook [2 ]
Lee, Jinhee [3 ]
Ko, Sanghoon [1 ]
机构
[1] Sejong Univ, Dept Food Sci & Technol, Seoul 143747, South Korea
[2] Kyung Hee Univ, Sch Management, Seoul 130701, South Korea
[3] Cha Univ, Dept Food Sci & Biotechnol, Songnam, Gyeonggi Do, South Korea
基金
新加坡国家研究基金会;
关键词
Curcumin; Catechin; Co-loading; Water-in-oil-in-water emulsion; Beverage; GREEN TEA CATECHINS; STABILITY; DELIVERY; VITRO; OPTIMIZATION; GENISTEIN; BEHAVIOR; GALLATE;
D O I
10.1016/j.jff.2015.03.013
中图分类号
TS2 [食品工业];
学科分类号
100403 [营养与食品卫生学];
摘要
Curcumin and catechin are nutraceuticals and natural health products that have shown several health benefits. However, due to their unstable nature, these compounds cannot be included in food products as such. The prime objective of the current study was to examine the formulation factors that determine the stability of these nutraceuticals and their carrier systems as well as to fabricate water-in-oil-in-water emulsions (W/O/W) to prevent the degradation of both curcumin and catechin in beverage systems. The fabricated emulsion had a volume-weighted mean diameter (d(43)) of similar to 4 mu m, with an encapsulation efficiency of >90%. Encapsulating the catechin within the inner aqueous phase of the double emulsion increased the stability of catechin by >20% at 23 +/- 2 degrees C and by >40% at 4 degrees C after 15 days of incubation, as compared to free catechin. In the case of curcumin, >80% was detected after incubation in the beverage system in the form of emulsions, whereas it was reduced to similar to 40% in the case of free curcumin. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:35 / 43
页数:9
相关论文
共 30 条
[1]
Co-delivery of hydrophobic curcumin and hydrophilic catechin by a water-in-oil-in-water double emulsion [J].
Aditya, N. P. ;
Aditya, Sheetal ;
Yang, Hanjoo ;
Kim, Hye Won ;
Park, Sung Ook ;
Ko, Sanghoon .
FOOD CHEMISTRY, 2015, 173 :7-13
[2]
Development and evaluation of lipid nanocarriers for quercetin delivery: A comparative study of solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), and lipid nanoemulsions (LNE) [J].
Aditya, N. P. ;
Macedo, Ana Sofia ;
Doktorovov, Slavomira ;
Souto, Efiana B. ;
Kim, Saehoon ;
Chang, Pahn-Shick ;
Ko, Sanghoon .
LWT-FOOD SCIENCE AND TECHNOLOGY, 2014, 59 (01) :115-121
[3]
Antiangiogenic effect of combined treatment with curcumin and genistein on human prostate cancer cell line [J].
Aditya, N. P. ;
Shim, Myeongkuk ;
Yang, Hanjoo ;
Lee, YoungJoo ;
Ko, Sanghoon .
JOURNAL OF FUNCTIONAL FOODS, 2014, 8 :204-213
[4]
Advances in nanomedicines for malaria treatment [J].
Aditya, N. P. ;
Vathsala, P. G. ;
Vieira, V. ;
Murthy, R. S. R. ;
Souto, E. B. .
ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2013, 201 :1-17
[5]
Curcumin and Genistein Coloaded Nanostructured Lipid Carriers: in Vitro Digestion and Antiprostate Cancer Activity [J].
Aditya, N. P. ;
Shim, Myeongkuk ;
Lee, Inae ;
Lee, YoungJoo ;
Im, Moo-Hyeog ;
Ko, Sanghoon .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2013, 61 (08) :1878-1883
[6]
Curcuminoids-loaded liposomes in combination with arteether protects against Plasmodium berghei infection in mice [J].
Aditya, N. P. ;
Chimote, Geetanjali ;
Gunalan, Karthigayan ;
Banerjee, Rinti ;
Patankar, Swati ;
Madhusudhan, Basavaraj .
EXPERIMENTAL PARASITOLOGY, 2012, 131 (03) :292-299
[7]
Optimization of water-in-oil-in-water microencapsulated β-galactosidase by response surface methodology [J].
Ahn, Sung-Il ;
Lee, Yun-Kyung ;
Kwak, Hae-Soo .
JOURNAL OF MICROENCAPSULATION, 2013, 30 (05) :460-469
[8]
Encapsulation of flavonoid in multiple emulsion using spinning disc reactor technology [J].
Akhtar, Mahmood ;
Murray, Brent S. ;
Afeisume, Ehihumeme I. ;
Khew, Shiow H. .
FOOD HYDROCOLLOIDS, 2014, 34 (01) :62-67
[9]
Effect of aqueous pH and electrolyte concentration on structure, stability and flow behavior of non-ionic surfactant based solid lipid nanoparticles [J].
Choi, Kyeong-Ok ;
Aditya, N. P. ;
Ko, Sanghoon .
FOOD CHEMISTRY, 2014, 147 :239-244
[10]
Effective use of reducing agents and nanoparticle encapsulation in stabilizing catechins in alkaline solution [J].
Dube, Admire ;
Ng, Ken ;
Nicolazzo, Joseph A. ;
Larson, Ian .
FOOD CHEMISTRY, 2010, 122 (03) :662-667