Regiochemical and stereochemical course of the reaction catalyzed by the fosfomycin resistance protein, FosA

被引：20

作者：

Bernat, BA

Laughlin, LT

Armstrong, RN ^{[1
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Sch Med, Dept Biochem, Nashville, TN 37232 USA

[2] Vanderbilt Univ, Med Ctr, Sch Med, Dept Chem, Nashville, TN 37232 USA

[3] Vanderbilt Univ, Med Ctr, Sch Med, Ctr Mol Toxicol, Nashville, TN 37232 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 11期

关键词：

D O I：

10.1021/jo980014b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：3778 / 3780

页数：3

共 12 条

[1] FORMATION OF AN ADDUCT BETWEEN FOSFOMYCIN AND GLUTATHIONE - A NEW MECHANISM OF ANTIBIOTIC-RESISTANCE IN BACTERIA [J].

ARCA, P ;

RICO, M ;

BRANA, AF ;

VILLAR, CJ ;

HARDISSON, C ;

SUAREZ, JE .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1988, 32 (10) :1552-1556

[2] PURIFICATION OF A GLUTATHIONE S-TRANSFERASE THAT MEDIATES FOSFOMYCIN RESISTANCE IN BACTERIA [J].

ARCA, P ;

HARDISSON, C ;

SUAREZ, JE .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1990, 34 (05) :844-848

[3] Structure, catalytic mechanism, and evolution of the glutathione transferases [J].

Armstrong, RN .

CHEMICAL RESEARCH IN TOXICOLOGY, 1997, 10 (01) :2-18

[4] Fosfomycin resistance protein (FosA) is a manganese metalloglutathione transferase related to glyoxalase I and the extradiol dioxygenases [J].

Bernat, BA ;

Laughlin, LT ;

Armstrong, RN .

BIOCHEMISTRY, 1997, 36 (11) :3050-3055

[5] PHOSPHONOMYCIN - STRUCTURE AND SYNTHESIS [J].

CHRISTENSEN, BG ;

LEANZA, WJ ;

BEATTIE, TR ;

PATCHETT, AA ;

ARISON, BH ;

ORMOND, RE ;

KUEHL, FA ;

ALBERSSC.G ;

JARDETZKY, O .

SCIENCE, 1969, 166 (3901) :123-+

[6] DESIGN AND SYNTHESIS OF NEW TRANSITION-STATE ANALOG INHIBITORS OF ASPARTATE-TRANSCARBAMYLASE [J].

FARRINGTON, GK ;

KUMAR, A ;

WEDLER, FC .

JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (11) :1668-1673

[7] PHOSPHONOMYCIN, A NEW ANTIBIOTIC PRODUCED BY STRAINS OF STREPTOMYCES [J].

HENDLIN, D ;

STAPLEY, EO ;

JACKSON, M ;

WALLICK, H ;

MILLER, AK ;

WOLF, FJ ;

MILLER, TW ;

CHAIET, L ;

KAHAN, FM ;

FOLTZ, EL ;

WOODRUFF, HB .

SCIENCE, 1969, 166 (3901) :122-&

[8]

JONES PG, 1981, CHEM BR, V17, P223

[9] MECHANISM OF ACTION OF FOSFOMYCIN (PHOSPHONOMYCIN) [J].

KAHAN, FM ;

KAHAN, JS ;

CASSIDY, PJ ;

KROPP, H .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1974, 235 (MAY10) :364-386

[10] KINETICS, STOICHIOMETRY, AND IDENTIFICATION OF THE REACTIVE THIOLATE IN THE INACTIVATION OF UDP-GLCNAC ENOLPYRUVOYL TRANSFERASE BY THE ANTIBIOTIC FOSFOMYCIN [J].

MARQUARDT, JL ;

BROWN, ED ;

LANE, WS ;

HALEY, TM ;

ICHIKAWA, Y ;

WONG, CH ;

WALSH, CT .

BIOCHEMISTRY, 1994, 33 (35) :10646-10651

← 1 2 →