Bullous pemphigoid - A report of 86 cases from Taiwan

被引:27
作者
Chang, YT
Liu, HN
Wong, CK
机构
[1] VET GEN HOSP,DEPT DERMATOL,TAIPEI 11217,TAIWAN
[2] NATL YANG MING UNIV,DEPT DERMATOL,TAIPEI,TAIWAN
关键词
D O I
10.1111/j.1365-2230.1996.tb00005.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We reviewed 86 cases of bullous pemphigoid and the results were compared with those reported in the literature. Seventy-eight per cent of the patients developed generalized blisters and 22% had localized blisters, including three cases of dyshidrosiform pemphigoid and one case of pretibial pemphigoid. Oral mucosal involvement was noticed in 12.8% of the patients. Fifteen per cent of the patients had internal malignancies but the incidence was not significantly different from the control group. Direct immunofluorescence in our series showed a high positive rate of 98.8%. Indirect immunofluorescence was positive in 48.1% of the 54 patients in whom this was carried out. Peripheral blood eosinophilia was observed in 22.1% of the patients. Prednisolone alone or in combination with immunosuppressive agents was the mainstay of treatment. Treatment side-effects was observed in 33% of the patients. Thirty pel cent of the patients had a complete remission after a mean follow-up period of 26.9 months.
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页码:20 / 22
页数:3
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