Distribution and daily variations of PACAP in the chicken brain

被引:34
作者
Józsa, R
Somogyvári-Vigh, A
Reglödi, D
Hollósy, T
Arimura, A
机构
[1] Tulane Univ, Dept Med, New Orleans, LA 70112 USA
[2] Univ Pecs, Dept Anat, H-7624 Pecs, Hungary
[3] Tulane Univ, Hebert Ctr, US Japan Biomed Res Labs, Belle Chasse, LA 70037 USA
基金
匈牙利科学研究基金会;
关键词
PACAP; chicken; daily variation; radioimmunoassay;
D O I
10.1016/S0196-9781(01)00477-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Levels of PACAP38 were measured in different areas of the chicken brain under various lighting conditions by radioimmunoassay (RIA). Selected groups of animals were maintained under light for 14 h alternating with 10 h of darkness (LD), reversed lighting conditions (DL) and constant light (LL) or constant dark (DD). Daily variations of PACAP levels were observed in the brainstem, diencephalon, telencephalon and retina. In the brainstem and diencephalon, levels of PACAP increased during subjective nighttime, except in the DL group where levels were elevated between 15-21 h. In the telencephalon, the lowest level of PACAP was measured between 12-21 h except in the DL group where two peaks occurred at 18 and 03 h. In the retina, all 4 groups showed a similar level and pattern, with lowest levels during midday hours. No daily variation was observed in the pineal gland, According to the present observations, it is suggested that PACAP levels differ in several areas of the chicken brain under various lighting conditions and photic stimuli do not appear to be the main regulators of the circadian variations of PACAP. (C) 2001 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:1371 / 1377
页数:7
相关论文
共 40 条
[1]   Long-term enhancement of REM sleep by the pituitary adenylyl cyclase-activating polypeptide (PACAP) in the pontine reticular formation of the rat [J].
Ahnaou, A ;
Basille, M ;
Gonzalez, B ;
Vaudry, H ;
Hamon, M ;
Adrien, J ;
Bourgin, P .
EUROPEAN JOURNAL OF NEUROSCIENCE, 1999, 11 (11) :4051-4058
[2]   TISSUE DISTRIBUTION OF PACAP AS DETERMINED BY RIA - HIGHLY ABUNDANT IN THE RAT-BRAIN AND TESTES [J].
ARIMURA, A ;
SOMOGYVARIVIGH, A ;
MIYATA, A ;
MIZUNO, K ;
COY, DH ;
KITADA, C .
ENDOCRINOLOGY, 1991, 129 (05) :2787-2789
[3]   Perspectives on pituitary adenylate cyclase activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous systems [J].
Arimura, A .
JAPANESE JOURNAL OF PHYSIOLOGY, 1998, 48 (05) :301-331
[4]   Calbindin-D28k immunoreactivity in the suprachiasmatic nucleus and the circadian response to constant light in the rat [J].
Arvanitogiannis, A ;
Robinson, B ;
Beaulé, C ;
Amir, S .
NEUROSCIENCE, 2000, 99 (03) :397-401
[5]   Circadian changes in PACAP type 1 (PAC1) receptor mRNA in the rat suprachiasmatic and supraoptic nuclei [J].
Cagampang, FRA ;
Piggins, HD ;
Sheward, WJ ;
Harmar, AJ ;
Coen, CW .
BRAIN RESEARCH, 1998, 813 (01) :218-222
[6]   Pituitary adenylyl cyclase-activating peptide: A pivotal modulator of glutamatergic regulation of the suprachiasmatic circadian clock [J].
Chen, D ;
Buchanan, GF ;
Ding, JM ;
Hannibal, J ;
Gillette, MU .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (23) :13468-13473
[7]  
Czeisler CA, 1999, RECENT PROG HORM RES, V54, P97
[8]   MAGNETIC-FIELDS ABOLISH NYCHTHEMERAL RHYTHMICITY OF RESPONSES OF PURKINJE-CELLS TO THE PINEAL HORMONE MELATONIN IN THE PIGEONS CEREBELLUM [J].
DEMAINE, C ;
SEMM, P .
NEUROSCIENCE LETTERS, 1986, 72 (02) :158-162
[9]   Day-night variation of pituitary adenylate cyclase-activating polypeptide (PACAP) level in the rat suprachiasmatic nucleus [J].
Fukuhara, C ;
Suzuki, N ;
Matsumoto, Y ;
Nakayama, Y ;
Aoki, K ;
Tsujimoto, G ;
Inouye, SIT ;
Masuo, Y .
NEUROSCIENCE LETTERS, 1997, 229 (01) :49-52
[10]   Pituitary adenylate cyclase-activating polypeptide rhythm in the rat pineal gland [J].
Fukuhara, C ;
Inouye, SIT ;
Matsumoto, Y ;
Tsujimoto, G ;
Aoki, K ;
Masuo, Y .
NEUROSCIENCE LETTERS, 1998, 241 (2-3) :115-118