One-pot catalytic synthesis of 2-(1,2-dihydroxypropyl)phenol derivatives from 2-allylphenols in aqueous media

被引：26

作者：

Chevrin, C ^{[1
]}

Le Bras, J ^{[1
]}

Hénin, F ^{[1
]}

Muzart, J ^{[1
]}

机构：

[1] Univ Reims, CNRS, UMR React Select & Applicat, F-51687 Reims, France

来源：

SYNTHESIS-STUTTGART | 2005年 / 15期

关键词：

alcohols; oxidations; phenols; palladium; epoxidations;

D O I：

10.1055/s-2005-872175

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Catalytic amounts of the hydrophilic ligand [(HOCH2CH2NHCOCH2)(2)NCH2](2) and palladium(II) salts, in the presence of hydrogen peroxide, water and alcohol, allow the direct transformation of 2-allylphenols into 2-(1,2-dihydroxypropyl)phenol derivatives. The mechanism involves sequential isomerisation, epoxidation, and oxirane-opening.

引用

页码：2615 / 2618

页数：4

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