SERS-fluorescent encoded particles as dual-mode optical probes

被引:52
作者
Alvarez-Puebla, Ramon A. [1 ,2 ]
Pazos-Perez, Nicolas [1 ]
Guerrini, Luca [1 ]
机构
[1] Univ Rovira & Virgili, Dept Quim Fis & Inorgan EMaS, Carrer Marcelli Domingo S-N, E-43007 Tarragona, Spain
[2] ICREA, Passeig Lluis Co 23, Barcelona 08010, Spain
关键词
Surface-enhanced Raman scattering; Fluorescence; Nanoparticles; Plasmonics; Optical sensing; Bio-imaging; ENHANCED RAMAN-SCATTERING; QUANTUM DOTS; IN-VITRO; NANOPARTICLES; NANOPROBES; MULTIPLEX; TAGS; SPECTROSCOPY; COMPOSITE; NANOSTRUCTURES;
D O I
10.1016/j.apmt.2018.07.007
中图分类号
T [工业技术];
学科分类号
120111 [工业工程];
摘要
Dual-mode optical platforms combining fluorescence (or metal-enhanced fluorescence, MEF) and surface-enhanced Raman scattering (SERS) signals into a single probe are emerging as powerful sensing analytical tools, especially in biomedical applications. SERS-fluorescence encoded particles (SFEPs) combine the unique advantages of fluorescence spectroscopy for the rapid read-out over a large area with the high-level of multiplexing and specificity of SERS. This review aims to provide a detailed summary and a critical discussion on the developments of these materials. This will start by highlighting fundamental aspects of the two techniques, then presenting their main building units and corresponding assembling designs and, finally, providing illustrative examples of potential applications. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1 / 14
页数:14
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