Induced Pluripotent Stem Cells: Past, Present, and Future

被引：525

作者：

Yamanaka, Shinya ^{[1
,2
]}

机构：

[1] Kyoto Univ, Ctr iPS Cell Res & Applicat, Kyoto 6068507, Japan

[2] Gladstone Inst Cardiovasc Dis, San Francisco, CA 94158 USA

来源：

CELL STEM CELL | 2012年 / 10卷 / 06期

关键词：

FAMILIAL ALZHEIMERS-DISEASE; GENE-EXPRESSION; SOMATIC-CELLS; DIRECT CONVERSION; HUMAN FIBROBLASTS; IPS CELLS; HUMAN ES; MOUSE; GENERATION; DIFFERENTIATION;

D O I：

10.1016/j.stem.2012.05.005

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

The development of iPSCs reflected the merging of three major scientific streams and has in turn led to additional new branches of investigation. However, there is still debate about whether iPSCs are functionally equivalent to ESCs. This question should be answered only by science, not by politics or business.

引用

页码：678 / 684

页数：7

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