Malettinin A:: a new antifungal tropolone from an unidentified fungal colonist of Hypoxylon stromata (NRRL 29110)

被引:34
作者
Angawi, RF
Swenson, DC
Gloer, JB [1 ]
Wicklow, DT
机构
[1] Univ Iowa, Dept Chem, Iowa City, IA 52242 USA
[2] USDA, Mycotoxin Res Unit, Natl Ctr Agr Utilizat Res, Peoria, IL 61604 USA
基金
美国国家科学基金会;
关键词
D O I
10.1016/j.tetlet.2003.08.057
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Malettinin A (1) has been isolated from cultures of an unidentified fungus encountered as a colonist of Hypoxylon stromata. The structure of 1 was proposed by analysis of NMR and MS data, and confirmed by X-ray diffraction analysis of a methanol adduct. Malettinin A shows significant activity in assays against Aspergillus flavus. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:7593 / 7596
页数:4
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