Transmission- and side-detection configurations in ultrasound-modulated optical tomography of thick biological tissues

被引：12

作者：

Li, J ^{[1
]}

Sakadzic, S ^{[1
]}

Ku, G ^{[1
]}

Wang, LHV ^{[1
]}

机构：

[1] Texas A&M Univ, Opt Imaging Lab, Dept Biomed Engn, College Stn, TX 77843 USA

来源：

APPLIED OPTICS | 2003年 / 42卷 / 19期

关键词：

D O I：

10.1364/AO.42.004088

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Ultrasound-modulated optical tomography of thick biological tissues was studied based on speckle-contrast detection. Speckle decorrelation was investigated with biological tissue samples of various thicknesses. Images of optically absorbing objects buried in biological tissue samples with thicknesses up to 50 mm were obtained in a transmission-detection configuration. The image contrast was more than 30%, and the spatial resolution was approximately 2 mm. In addition, a side-detection scheme along with two specific configurations were examined, and the advantages were demonstrated. Experimental results implied feasibility of applying the ultrasound-modulation technique to characterize optical properties in inhomogeneous biological tissues. (C) 2003 Optical Society of America.

引用

页码：4088 / 4094

页数：7

共 19 条

[1]

American National Standards Institute, 2000, AM NAT STAND CENTR P

[2] Detection of inhomogeneities with ultrasound tagging of light [J].

Granot, E ;

Lev, A ;

Kotler, Z ;

Sfez, BG ;

Taitelbaum, H .

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 2001, 18 (08) :1962-1967

[3] Direct, noninvasive detection of photon density in turbid media [J].

Lev, A ;

Sfez, BG .

OPTICS LETTERS, 2002, 27 (07) :473-475

[4] Ultrasound tagged light imaging in turbid media in a reflectance geometry [J].

Lev, A ;

Kotler, Z ;

Sfez, BG .

OPTICS LETTERS, 2000, 25 (06) :378-380

[5] Ultrasonic tagging of photon paths in scattering media:: parallel speckle modulation processing [J].

Lévêque, S ;

Boccara, AC ;

Lebec, M ;

Saint-Jalmes, H .

OPTICS LETTERS, 1999, 24 (03) :181-183

[6] Three-dimensional acousto-optic imaging in biological tissues with parallel signal processing [J].

Lévêque-Fort, S .

APPLIED OPTICS, 2001, 40 (07) :1029-1036

[7] In situ local tissue characterization and imaging by backscattering acousto-optic imaging [J].

Lévêque-Fort, S ;

Selb, J ;

Pottier, L ;

Boccara, AC .

OPTICS COMMUNICATIONS, 2001, 196 (1-6) :127-131

[8] Methods for parallel-detection-based ultrasound-modulated optical tomography [J].

Li, J ;

Wang, LV .

APPLIED OPTICS, 2002, 41 (10) :2079-2084

[9] Ultrasound-modulated optical tomography of biological tissue by use of contrast of laser speckles [J].

Li, J ;

Ku, G ;

Wang, LHV .

APPLIED OPTICS, 2002, 41 (28) :6030-6035

[10] Anisotropy in the absorption and scattering spectra of chicken breast tissue [J].

Marquez, G ;

Wang, LHV ;

Lin, SP ;

Schwartz, JA ;

Thomsen, SL .

APPLIED OPTICS, 1998, 37 (04) :798-804

← 1 2 →