Three-dimensional acousto-optic imaging in biological tissues with parallel signal processing

被引：38

作者：

Lévêque-Fort, S

机构：

[1] Ecole Super Phys & Chim Ind Ville Paris, CNRS, Unite Propre A0005, Lab Opt Phys, F-75005 Paris, France

[2] Univ Paris 06, F-75005 Paris, France

来源：

APPLIED OPTICS | 2001年 / 40卷 / 07期

关键词：

D O I：

10.1364/AO.40.001029

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

An original acousto-optic method is described that allows one to reveal optical contrasts through biological tissues that are several centimeters thick with a millimeter-sized resolution. This technique is based on the interaction of scattered laser light with a focused ultrasonic field. The modulation depth of the optical speckle is related to local optical properties of the sample. Our parallel-processing approach to the demodulation of the speckle improves the observed degree of modulation by 2 orders of magnitude and quickly yields a good statistical value. Optically absorbing objects were imaged inside 35-mm-thick biological tissues. (C) 2001 Optical Society of America

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页码：1029 / 1036

页数：8

相关论文

共 18 条

[1] SCATTERING OF DIFFUSE PHOTON DENSITY WAVES BY SPHERICAL INHOMOGENEITIES WITHIN TURBID MEDIA - ANALYTIC SOLUTION AND APPLICATIONS [J].

BOAS, DA ;

OLEARY, MA ;

CHANCE, B ;

YODH, AG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (11) :4887-4891

[2] In vivo ultrahigh-resolution optical coherence tomography [J].

Drexler, W ;

Morgner, U ;

Kärtner, FX ;

Pitris, C ;

Boppart, SA ;

Li, XD ;

Ippen, EP ;

Fujimoto, JG .

OPTICS LETTERS, 1999, 24 (17) :1221-1223

[3] Picometric profilometry .2. Multi detector approach and multiplexed lock-in detection [J].

Gleyzes, P ;

Guernet, F ;

Boccara, AC .

JOURNAL OF OPTICS-NOUVELLE REVUE D OPTIQUE, 1995, 26 (06) :251-265

[4] Simultaneous reconstruction of absorption and scattering images by multichannel measurement of purely temporal data [J].

Hebden, JC ;

Schmidt, FEW ;

Fry, ME ;

Schweiger, M ;

Hillman, EMC ;

Delpy, DT ;

Arridge, SR .

OPTICS LETTERS, 1999, 24 (08) :534-536

[5] Three-dimensional photoacoustic imaging of blood vessels in tissue [J].

Hoelen, CGA ;

de Mul, FFM ;

Pongers, R ;

Dekker, A .

OPTICS LETTERS, 1998, 23 (08) :648-650

[6] Acousto-optic tomography with multiply scattered light [J].

Kempe, M ;

Larionov, M ;

Zaslavsky, D ;

Genack, AZ .

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1997, 14 (05) :1151-1158

[7] ULTRASONIC MODULATION OF MULTIPLY SCATTERED-LIGHT [J].

LEUTZ, W ;

MARET, G .

PHYSICA B, 1995, 204 (1-4) :14-19

[8] Ultrasonic tagging of photon paths in scattering media:: parallel speckle modulation processing [J].

Lévêque, S ;

Boccara, AC ;

Lebec, M ;

Saint-Jalmes, H .

OPTICS LETTERS, 1999, 24 (03) :181-183

[9]

LEVEQUE S, 1998, OSA TRENDS OPTICS PH, V23, P397

[10]

LEWINER J, 1984, IMAGERIE CORPS HUMAI