Front line tests for the investigation of suspected porphyria

被引：87

作者：

Deacon, AC

Elder, GH

机构：

[1] Cardiff Univ, Dept Med Biochem, Cardiff CF14 4XN, S Glam, Wales

[2] Kings Coll Hosp London, Dept Clin Biochem, London SE5 9RS, England

来源：

JOURNAL OF CLINICAL PATHOLOGY | 2001年 / 54卷 / 07期

关键词：

porphyria; haem biosynthesis; best practice guidelines;

D O I：

10.1136/jcp.54.7.500

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The porphyrias are uncommon disorders of haem biosynthesis and their effective management requires prompt and accurate diagnosis. This article describes methods for the determination of urinary porphobilinogen, urinary and faecal total porphyrins, and total porphyrins in erythrocytes and plasma that are suitable for use in non-specialist laboratories. The selection and interpretation of these methods, and the indications for further, more specialised, investigation are discussed.

引用

页码：500 / 507

页数：8

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[2]

BLAKE D, 1992, CLIN CHEM, V38, P96

[3]

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