Hospital-acquired pneumonia:: etiologic considerations

被引:22
作者
Alcón, A [1 ]
Fàbregas, N [1 ]
Torres, A [1 ]
机构
[1] Univ Barcelona, Hosp Clin Barcelona, Anesthesiol Serv, Surg Intens Care Unit, E-08036 Barcelona, Spain
关键词
D O I
10.1016/S0891-5520(03)00074-6
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The development of pneumonia requires the pathogen to reach the alveoli and the host defenses to be overwhelmed, either by microorganism virulence or by inoculum size. Different microorganisms can be found depending on the onset time of pneumonia and on the local pattern variation encountered between different institutions and countries. A very important, unresolved issue is the definition of early and late-onset pneumonia. It still remains uncertain from the literature whether the given threshold refers to the number of days in hospital or to the number of days following intubation. Noninvasive ventilation is demonstrating that the term "ventilator-associated pneumonia" is perhaps inaccurate and should be referred to as "intubation-associated pneumonia."
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页码:679 / +
页数:18
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