Trace element concentrations in hair of healthy Chinese centenarians

被引:48
作者
Li, Yonghua [1 ]
Yang, Linsheng [1 ]
Wang, Wuyi [1 ]
Li, Hairong [1 ]
Lv, Jinmei [1 ]
Zou, Xiaoyan [1 ]
机构
[1] Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Beijing 100101, Peoples R China
基金
美国国家科学基金会;
关键词
Ageing; Centenarians; Hair; Human health; Trace element; SCALP HAIR; GREEK CENTENARIANS; REFERENCE VALUES; ELDERLY-PEOPLE; POPULATION; COPPER; BLOOD; SERUM; ZINC; DEFICIENCY;
D O I
10.1016/j.scitotenv.2011.01.017
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Trace element concentrations, as indicators of micronutrient status of healthy centenarians, have not been widely analyzed. This study aimed to assess trace element concentrations in the hair of healthy centenarians. The effects of gender and age on element concentrations were also investigated. Eleven trace elements (Al, Ba, Cd, Cr, Cu, Fe, Mo, Pb, Se, Sr and Zn) in the scalp hair of 107 healthy Chinese centenarians were examined. The overall reference values (RVs) in mg/kg for the hair concentrations of trace elements in centenarians were as follows: Al, 14.95; Ba, 2.68; Cd, 0.06; Cr, 0.59; Cu, 6.21); Fe, 19.37; Mo, 0.50; Pb, 4.64; Se, 0.37; Sr, 4.84; and Zn, 154.37. Data analysis found that only Cu and Zn concentrations show a normal distribution, and there is no significant difference between males and females in any element except Zn. However, the levels of Al, Cd, Cr, Fe, Mo, Pb decrease and the levels of Ba, Cu, Se, Sr, Zn increase with age in the centenarian cohort. Results also revealed that sufficient Zn and Se concentrations as well as low exposure to heavy metals pollution contribute to the longevity of centenarians. The results imply the possibility of manipulating trace element concentrations, especially Zn and Se concentrations in tissues, as a means for therapeutic modality in geriatric disease. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:1385 / 1390
页数:6
相关论文
共 44 条
  • [1] *ADSTR, PRIOR LIST HAZ SUBST
  • [2] Status of essential trace metals in biological samples of diabetic mother and their neonates
    Afridi, Hassan Imran
    Kazi, Tasneem Gul
    Kazi, Naveed
    Baig, Jamil Ahmed
    Jamali, Mohammad Khan
    Arain, Mohammad Balal
    Sarfraz, Raja Adil
    Sheikh, Hafeez-ur-Rehman
    Kandhro, Ghulam Abbas
    Shah, Abdul Qadir
    [J]. ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2009, 280 (03) : 415 - 423
  • [3] Dementia is not inevitable: A population-based study of Danish centenarians
    Andersen-Ranberg, K
    Vasegaard, L
    Jeune, B
    [J]. JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES, 2001, 56 (03): : P152 - P159
  • [4] Human biomonitoring: State of the art
    Angerer, Juergen
    Ewers, Ulrich
    Wilhelm, Michael
    [J]. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2007, 210 (3-4) : 201 - 228
  • [5] Establishing baseline levels of trace elements in blood and skin of bottlenose dolphins in Sarasota Bay, Florida: Implications for non-invasive monitoring
    Bryan, Colleen E.
    Christopher, Steven J.
    Balmer, Brian C.
    Wells, Randall S.
    [J]. SCIENCE OF THE TOTAL ENVIRONMENT, 2007, 388 (1-3) : 325 - 342
  • [6] *CHIN NBS, 2002, 5 CENS CHIN
  • [7] Reference values for hair minerals of Polish students
    Chojnacka, Katarzyna
    Zielinska, Agnieszka
    Gorecka, Helena
    Dobrzanski, Zbigniew
    Gorecki, Henryk
    [J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2010, 29 (03) : 314 - 319
  • [8] Effect of heavy metal stress on proline, malondialdehyde, and superoxide dismutase activity in the cyanobacterium Spirulina platensis-S5
    Choudhary, Meenakshi
    Jetley, Umesh Kumar
    Khan, Mohammed Abash
    Zutshi, Sunaina
    Fatma, Tasneem
    [J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2007, 66 (02) : 204 - 209
  • [9] Assessment of the health status of Greek centenarians
    Darviri, Christina
    Demakakos, Panayotes
    Charizani, Fotini
    Tigani, Xanthi
    Tsiou, Chrysoula
    Chalamandaris, Alexandros G.
    Tsagkari, Christina
    Chliaoutakis, Joannnes
    [J]. ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2008, 46 (01) : 67 - 78
  • [10] Evert J, 2003, J GERONTOL A-BIOL, V58, P232