Spatial memory and learning in transgenic mice: Fact or artifact?

被引：140

作者：

Wolfer, DP ^{[1
]}

Stagljar-Bozicevic, M

Errington, ML

Lipp, HP

机构：

[1] Univ Zurich, Inst Anat, Lab Neuroanat & Behav, CH-8057 Zurich, Switzerland

[2] Natl Inst Med Res, Div Neurophysiol, London NW7 1AA, England

来源：

NEWS IN PHYSIOLOGICAL SCIENCES | 1998年 / 13卷

关键词：

D O I：

10.1152/physiologyonline.1998.13.3.118

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Spatial learning of transgenic mice is often assessed in the Morris watermaze, where mice must use distant cues to locate a submerged platform. Such learning is confounded by species-specific noncognitive swimming strategies. Factor analysis permits cognitive and noncognitive strategies to be disentangled and their association with electrophysiological phenomena to be investigated.

引用

页码：118 / 123

页数：6