RNA silencing and antiviral defense in plants

被引：139

作者：

Wang, MB

Metzlaff, M

机构：

[1] CSIRO Plant Ind, Canberra, ACT 2601, Australia

[2] Bayer BioSci NV, B-9052 Ghent, Belgium

来源：

CURRENT OPINION IN PLANT BIOLOGY | 2005年 / 8卷 / 02期

关键词：

D O I：

10.1016/j.pbi.2005.01.006

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Much progress has been made recently in identifying the molecular components of RNA silencing in plants, and in understanding their roles in the biogenesis of small interfering RNAs and microRNAs, in RNA-directed DNA methylation, and in RNA-mediated antiviral defense. However, many crucial questions remain unanswered. What are the molecular bases of sense and antisense transgene-mediated silencing? Why does silencing only appear to spread through transgenes? Plant viruses encode silencing suppressors to counteract host RNA silencing, and some of these suppressors affect microRNA accumulation and function and hence normal plant development. Is viral pathogenicity determined, partly or entirely, by their silencing suppressor activity?

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收藏

页码：216 / 222

页数：7

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