One-pot preparation of pyranoquinolinones by ytterbium(III) trifluoromethanesulfonate-catalyzed reactions:: Efficient synthesis of flindersine, N-methylflindersine, and zanthosimuline natural products

被引：39

作者：

Lee, YR ^{[1
]}

Kweon, HI

Koh, WS

Min, KR

Kim, YS

Lee, SH

机构：

[1] Yeungnam Univ, Sch Chem Engn & Technol, Kyongsan 712749, South Korea

[2] Chungbuk Natl Univ, Coll Pharm, Cheongju 361763, South Korea

[3] Yeungnam Univ, Coll Pharm, Kyongsan 712749, South Korea

来源：

SYNTHESIS-STUTTGART | 2001年 / 12期

关键词：

pyranoquinolinone alkaloids; Yb(OTf)(3); flindersine; N-methylflindersine; zanthosimuline;

D O I：

10.1055/s-2001-17516

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of pyranoquinolinones is achieved by ytterbium(III) triflate-catalyzed reaction of 4-hydroxy-2-quinolones with a variety of alpha,beta -unsaturated aldehydes in moderate yields. This new method has been applied to the synthesis of pyranoquinolinone alkaloids.

引用

页码：1851 / 1855

页数：5

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JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1999, (14) :2017-2023

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