Antiparasitic Therapy

被引:71
作者
Kappagoda, Shanthi [1 ,2 ,3 ]
Singh, Upinder [1 ,2 ]
Blackburn, Brian G. [1 ,2 ]
机构
[1] Stanford Univ, Div Infect Dis & Geog Med, Sch Med, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Internal Med, Sch Med, Stanford, CA 94305 USA
[3] Stanford Univ, Ctr Primary Care & Outcomes Res, Sch Med, Stanford, CA 94305 USA
基金
美国医疗保健研究与质量局;
关键词
TRANSMITTED HELMINTH INFECTIONS; INTESTINAL NEMATODE INFECTIONS; PLASMODIUM-FALCIPARUM MALARIA; WORLD CUTANEOUS LEISHMANIASIS; VISCERAL LEISHMANIASIS; COMBINATION THERAPY; RANDOMIZED-TRIAL; AMPHOTERICIN-B; CLINICAL-TRIAL; DOUBLE-BLIND;
D O I
10.4065/mcp.2011.0203
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Parasitic diseases affect more than 2 billion people globally and cause substantial morbidity and mortality, particularly among the world's poorest people. This overview focuses on the treatment of the major protozoan and helminth Infections In humans. Recent developments in antiparasitic therapy include the expansion of artemisinin-based therapies for malaria, new drugs for soil-transmitted heiminths and intestinal protozoa, expansion of the indications for antiparasitic drug treatment in patients with Chagas disease, and the use of combination therapy for leishmaniasis and human African trypanosomiasis.
引用
收藏
页码:561 / 583
页数:23
相关论文
共 132 条
[52]   ALBENDAZOLE IN HUMAN LOIASIS - RESULTS OF A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].
KLION, AD ;
MASSOUGBODJI, A ;
HORTON, J ;
EKOUE, S ;
LANMASSO, T ;
AHOUISSOU, NL ;
NUTMAN, TB .
JOURNAL OF INFECTIOUS DISEASES, 1993, 168 (01) :202-206
[53]   Albendazole and Mebendazole Administered Alone or in Combination with Ivermectin against Trichuris trichiura: A Randomized Controlled Trial [J].
Knopp, Stefanie ;
Mohammed, Khalfan A. ;
Speich, Benjamin ;
Hattendorf, Jan ;
Khamis, I. Simba ;
Khamis, Alipo N. ;
Stothard, J. Russell ;
Rollinson, David ;
Marti, Hanspeter ;
Utzinger, Juerg .
CLINICAL INFECTIOUS DISEASES, 2010, 51 (12) :1420-1428
[54]   Persistent and relapsing babesiosis in Immunocompromised patients [J].
Krause, Peter J. ;
Gewurz, Benjamin E. ;
Hill, David ;
Marty, Francisco M. ;
Vannier, Edouard ;
Foppa, Ivo M. ;
Furman, Richard R. ;
Neuhaus, Ellen ;
Skowron, Gail ;
Gupta, Shaili ;
McCalla, Carlo ;
Pesanti, Edward L. ;
Young, Mary ;
Heiman, Donald ;
Hsue, Gunther ;
Gelfand, Jeffrey A. ;
Wormser, Gary P. ;
Dickason, John ;
Bia, Frank J. ;
Hartman, Barry ;
Telford, Sam R., III ;
Christianson, Diane ;
Dardick, Kenneth ;
Coleman, Morton ;
Girotto, Jennifer E. ;
Spielman, Andrew .
CLINICAL INFECTIOUS DISEASES, 2008, 46 (03) :370-376
[55]   Atovaquone and azithromycin for the treatment of babesiosis. [J].
Krause, PJ ;
Lepore, T ;
Sikand, VK ;
Gadbaw, JJ ;
Burke, G ;
Telford, SR ;
Brassard, P ;
Pearl, D ;
Azlanzadeh, J ;
Christianson, D ;
McGrath, D ;
Spielman, A .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (20) :1454-1458
[56]   Successful treatment of niclosamide- and praziquantel-resistant beef tapeworm infection with nitazoxanide [J].
Lateef, Mohammad ;
Zargar, Showkat Ali ;
Khan, Abdul Rashid ;
Nazir, Muzzaffar ;
Shoukat, Abid .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2008, 12 (01) :80-82
[57]   Progressive chronic Chagas heart disease ten years after treatment with anti-Trypanosoma cruzi nitroderivatives [J].
Lauria-Pires, L ;
Braga, MS ;
Vexenat, AC ;
Nitz, N ;
Simoes-Barbosa, A ;
Tinoco, DL ;
Teixeira, ARL .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2000, 63 (3-4) :111-118
[58]  
LIU YH, 1991, CHINESE MED J-PEKING, V104, P27
[59]   Oral pentoxifylline combined with pentavalent antimony: A randomized trial for mucosal leishmaniasis [J].
Machado, Paulo R. L. ;
Lessa, Helio ;
Lessa, Marcus ;
Guimaraes, Luiz H. ;
Bang, Heejung ;
Ho, John L. ;
Carvalho, Edgar M. .
CLINICAL INFECTIOUS DISEASES, 2007, 44 (06) :788-793
[60]   COMPARATIVE EFFICACY OF DIETHYLCARBAMAZINE AND MEBENDAZOLE FOR THE TREATMENT OF HUMAN TOXOCARIASIS [J].
MAGNAVAL, JF .
PARASITOLOGY, 1995, 110 :529-533