Plant microtubule-associated proteins:: the HEAT is off in temperature-sensitive mor1

Microtubules perform essential functions in plant cells and govern, with other cytoskeletal elements, cell division, formation of cell walls and morphogenesis. For microtubules to perform their roles in the cell their organization and dynamics must be regulated and microtubule-associated proteins bear the main responsibility for these activities. We are just beginning to identify these plant microtubule-regulating proteins. Biochemical, molecular and genetic procedures have identified plant homologues of known microtubule-associated proteins, such as kinesins, katanin and XMAP215, and novel classes of plant microtubule-associated proteins, such as MAP65 and MAP190. Showing how these proteins coordinate the microtubule cytoskeleton in vivo is now the challenge. The recent identification and characterization of the Arabidopsis thaliana microtubule organization mutant, mor1, begins to address this challenge and here we highlight the significance of this work.