Validation studies and characterization of variant alleles at the short tandem repeat locus D12S391

被引：7

作者：

Junge, A ^{[1
]}

Madea, B ^{[1
]}

机构：

[1] Univ Bonn, Inst Legal Med, D-53111 Bonn, Germany

来源：

INTERNATIONAL JOURNAL OF LEGAL MEDICINE | 1998年 / 112卷 / 01期

关键词：

D12S391; population study; forensic application; sequence analysis; variant alleles;

D O I：

10.1007/s004140050202

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Validation studies were carried out on the short tandem repeat (STR) locus D12S391 including the determination of the allele frequencies, forensic application and sequence analysis of variant alleles. A total of 16 alleles were found in a population survey of 158 unrelated individuals from the Rhine area, none of which exceeded the 0.20 frequency level. In 316 alleles analysed so far 18 alleles were found with an incomplete repeat unit in the 5'-end of the repeat region. The statistical values were similar to those of other European populations and no deviation from Hardy-Weinberg equilibrium (HWE) was observed.

引用

页码：67 / 69

页数：3

共 13 条

[1]

Gene M, 1998, INT J LEGAL MED, V111, P52

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