Gold(I)-catalyzed cycloisomerization of 1,7-and 1,8-enynes: Application to the synthesis of a new allocolchicinoid

被引：51

作者：

Boyer, Francois-Didier ^{[3
]}

Le Goff, Xavier ^{[2
]}

Hanna, Issam ^{[1
]}

机构：

[1] Ecole Polytech, CNRS, UMR 7652, Synth Organ Lab, F-91128 Palaiseau, France

[2] Ecole Polytech, CNRS, UMR 7653, Lab Heteroatomes & Coordinat, F-91128 Palaiseau, France

[3] INRA, Unite Chim Biol, F-78026 Versailles, France

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 73卷 / 13期

关键词：

D O I：

10.1021/jo800797c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Gold(I)-catalyzed cycloisomerization of 1,7- and 1,8-enyne propargylic acetates afforded cyclopropyl derivatives containing seven- and eight-membered rings, respectively. This reaction was used for the synthesis of a new allocolchicinoid having a cyclopropane ring fused to the B seven-membered ring at the C6-C7 positions.

引用

页码：5163 / 5166

页数：4

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