Biodesulfurization of fossil fuels

被引：114

作者：

Gray, KA

Mrachko, GT

Squires, CH

机构：

[1] Dow Chem Co USA, San Diego, CA 92121 USA

[2] Diversa Corp, San Diego, CA 92121 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2003年 / 6卷 / 03期

关键词：

D O I：

10.1016/S1369-5274(03)00065-1

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Biotechnological techniques enabling the specific removal of sulfur from fossil fuels have been developed. In the past three years there have been important advances in the elucidation of the mechanisms of biodesulfurization; some of the most significant relate to the role of a flavin reductase, DszD, in the enzymology of desulfurization, and to the use of new tools that enable enzyme enhancement via DNA manipulation to influence both the rate and the substrate range of Dsz. Also, a clearer understanding of the unique desulfinase step in the pathway has begun to emerge.

引用

收藏

页码：229 / 235

页数：7

相关论文

共 53 条

[1] Chemostat approach for the directed evolution of biodesulfurization gain-of-function mutants [J].

Arensdorf, JJ ;

Loomis, AK ;

DiGrazia, PM ;

Monticello, DJ ;

Pienkos, PT .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2002, 68 (02) :691-698

[2] Directed evolution of biocatalysts [J].

Arnold, FH ;

Volkov, AA .

CURRENT OPINION IN CHEMICAL BIOLOGY, 1999, 3 (01) :54-59

[3] Citrobacter freundii tyrosine phenol-lyase:: the role of asparagine 185 in modulating enzyme function through stabilization of a quinonoid intermediate [J].

Barbolina, MV ;

Phillips, RS ;

Gollnick, PD ;

Faleev, NG ;

Demidkina, TV .

PROTEIN ENGINEERING, 2000, 13 (03) :207-215

[4] Desulfurization of light gas oil in immobilized-cell systems of Gordona sp CYKS1 and Nocardia sp CYKS2 [J].

Chang, JH ;

Chang, YK ;

Ryu, HW ;

Chang, HN .

FEMS MICROBIOLOGY LETTERS, 2000, 182 (02) :309-312

[5] SITE-DIRECTED MUTAGENESIS OF TYROSINE-71 TO PHENYLALANINE IN CITROBACTER-FREUNDII TYROSINE PHENOL-LYASE - EVIDENCE FOR DUAL ROLES OF TYROSINE-71 AS A GENERAL ACID CATALYST IN THE REACTION-MECHANISM AND IN COFACTOR BINDING [J].

CHEN, HY ;

DEMIDKINA, TV ;

PHILLIPS, RS .

BIOCHEMISTRY, 1995, 34 (38) :12276-12283

[6] DNA shuffling method for generating highly recombined genes and evolved enzymes [J].

Coco, WM ;

Levinson, WE ;

Crist, MJ ;

Hektor, HJ ;

Darzins, A ;

Pienkos, PT ;

Squires, CH ;

Monticello, DJ .

NATURE BIOTECHNOLOGY, 2001, 19 (04) :354-359

[7]

Czogalla C.-D.B., 1983, Sulfur Reports, V3, P121

[8]

Darzins A., 2000, U.S. Patent, Patent No. 6133016

[9] Analysis of bacterial community structure in sulfurous-oil-containing soils and detection of species carrying dibenzothiophene desulfurization (dsz) genes [J].

Duarte, GF ;

Rosado, AS ;

Seldin, L ;

de Araujo, W ;

van Elsas, JD .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2001, 67 (03) :1052-1062

[10]

Dudley M W, 1994, Bioorg Med Chem, V2, P681, DOI 10.1016/0968-0896(94)85018-6

← 1 2 3 4 5 6 →